Landiolol Injection

What is this medication?

LANDIOLOL (lan DYE oh lol) treats a fast or irregular heartbeat (arrhythmia). It is often used to treat a type of arrhythmia known as AFib (atrial fibrillation). It works by decreasing your heart rate, which decreases the amount of work your heart has to do. It belongs to a group of medications called beta-blockers.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): RAPIBLYK

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

• Asthma
• Circulation problems in fingers or toes (Raynaud syndrome)
• Diabetes
• Heart or blood vessel conditions, such as slow heartbeat, heart failure, heart block
• Kidney disease
• Liver disease
• Pheochromocytoma
• Thyroid disease
• An unusual or allergic reaction to landiolol, other medications, foods, dyes, or preservatives
• Pregnant or trying to get pregnant
• Breastfeeding

How should I use this medication?

This medication is infused into a vein. It is given by your care team in a hospital or clinic setting.

Talk to your care team about the use of this medication in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply.

What may interact with this medication?

• Certain medications for blood pressure, heart disease, irregular heartbeat
• MAOIs, such as Marplan, Nardil, and Parnate

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Your condition will be monitored carefully while you are receiving this medication.

You may need bloodwork done while you are taking this medication.

This medication may affect blood glucose levels. It can also mask the symptoms of low blood sugar, such as a rapid heartbeat and tremors. If you have diabetes, it is important to check your blood sugar often while you are taking this medication.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

• Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
• Heart failure—shortness of breath, swelling of the ankles, feet, or hands, sudden weight gain, unusual weakness or fatigue
• High potassium level—muscle weakness, fast or irregular heartbeat
• Low blood pressure—dizziness, feeling faint or lightheaded, blurry vision
• Slow heartbeat—dizziness, feeling faint or lightheaded, confusion, trouble breathing, unusual weakness or fatigue

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

• Pain, redness, or irritation at injection site

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

This medication is given in a hospital or clinic. It will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.